Our Research
At the Biosystems Engineering Lab, we focus on engineering microbial systems to produce biochemicals and bioremediate recalcitrant and toxic compounds. We put special effort into cellular reprogramming via genetic modifications integrating synthetic and systems biology along with adaptive evolution. We also pursue to establish novel bioprocesses utilizing low-value feedstocks as carbon substrates from various waste streams. Besides, we attempt to systematically dissect the metabolic operation of microbes —single and communities—through metabolic network reconstruction, 13C-based flux analysis, and integration of omics data into genome-scale metabolic models.
